Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-197-2
CAS number: -
The acute toxicity of epoxy resins was
investigated by Hine et al.(Hine, 1958). The effect of inhalation of the
two most fluid resins, EPON 562 and DGR, was tested on rats (male Long
evans) and mice (male Swiss webster) by an eight-hour exposure. Air was
saturated with EPON 562 at 20±2°C and at 30±1°C, and with DGR at 30±1°C,
by passage through the liquids in two fritted glass bubblers connected
in series. The animals were observed for the following 10 days, and
those that died were subjected to necropsy. At the end of the
observation period, the survivors were killed for necropsy, and sections
of their tissues were preserved in 10% formalin for histologic
examination. They found that neither compound caused death when rats
were exposed for eight hours to saturated vapours. The toxicity of the
derivative was slightly less than that of the parent compound. Gross
pathology was nonspecific, and the chief effect was that of local
irritation. There was no noticeable species variation among the rat,
mouse, and rabbit.
In conlusion the investigation of the
toxicology of certain epoxy resins, a new type of condensation plastic,
indicated that the epoxy resins are of a low order of toxicity. The
biological activity is considerably less than that of most monomers,
and, residing in the epoxy group, disappears on curing of the resins.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again