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EC number: 701-197-2
CAS number: -
Criteria for assessing PBT properties
are defined in Annex XIII, REACH Regulation (EC) No. 1907/2006. Further
details are laid down in ECHA Guidance on Information Requirements and
Chemical Safety Assessment; Chapter R.11: PBT Assessment (May 2008). The
assessment of PBT / vPvB properties is based upon a separate assessment
for each parameter (i.e. P or vP, B or B and T). Substances are only
assigned as PBT or vPvB when they fulfil the criteria for all three
properties (persistency, bioaccumulation and toxicity in case of PBT
substance) or both criteria (i.e. very persistent and very
bioaccumulative) in case of vPvB, respectively.
Due to results of the prolonged ready
biodegradability testing (55 days instead of 28 days) according to OECD
Guideline 301 F (Eisner, 2013), 1,2,3-Propanetriol, glycidyl ethers is
considered as persistent (P) but not very persistent (not vP).
The B criterion (bioaccumulative
substance) is not fulfilled, since the octanol-water partition
coefficient (logPow) was predicted as -2 (Chemservice S.A., 2012) and
the Bioconcentration factor (BCF) is far below the trigger value of 100
L/kg (3.16 L/kg, Chemservice S.A., 2012). Therefore, 1,2,3-Propanetriol,
glycidyl ethers can be considered as non-bioaccumulative (not B).
The target substance possesses no
potential to be long-term toxic towards freshwater invertebrates (NOEC
(21d): 8.2 mg/L; Liedkte, 2013). Experimental results from read-across
substances for 1,2,3-Propanetriol, glycidyl ethers are taken into
account in order to complete the T assessment of the target substance.
However, classification as carcinogenic (Category 2), mutagenic
(Category 2) and toxic for reproduction (Category 2) is warranted. Thus,
based on the criteria laid down in REACH Regulation (EC) 1207/2006
(Annex XIII), the substance has to be considered as toxic (T).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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