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EC number: 201-854-9
CAS number: 88-73-3
48 h after a single oral administration of 100 mg/kg bw of o-chloronitrobenzene to rabbits,
0.3 % of the administered dose was found in faeces as unabsorbed material which was
completely reduced to the chloroaniline;
in the urines collected each 24 h for 48 h the following metabolites of
o-chloronitrobenzene were detectable (expressed as per-
centages of the administered dose):
- ether glucuronide (42 %)
- ethereal sulphate (24 %)
- mercapturic acid (7 %)
- free chloroaniline (9 %)
(total accounted for: 82 %)
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