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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Basic data given: comparable to guideline. Adopted according to OECD SIDS. The original source is available and has been reviewed.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Quantitative Structure-Activity Relationships of Nitroaromatic Compounds to Four Aquatic Organisms.
Author:
Zhao Y-H, Yuan X, Ji G-D, Sheng L-X, Wang L-S
Year:
1997
Bibliographic source:
Chemosphere 34 (8): 1837 - 1844
Reference Type:
secondary source
Title:
1-Chloro-2-nitrobenzene CAS: 88-73-3, SIDS Initial Assessment Report
Author:
OECD
Year:
2001
Bibliographic source:
UNEP publications

Materials and methods

Test guideline
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Version / remarks:
(1984)
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): 2-Chloronitrobenzene
- Analytical purity: no data

Sampling and analysis

Analytical monitoring:
not specified

Test organisms

Test organisms (species):
other: Daphnia carinata
Details on test organisms:
TEST ORGANISM
- Age at study initiation: 6-24 hours
- Feeding during test: no

CULTURE
- Temperature: 22 ± 1 °C
- Type and amount of food: green alga
- Photoperiod: 14 h daylight / 10 h darkness

Study design

Test type:
static
Water media type:
freshwater
Total exposure duration:
48 h

Test conditions

Nominal and measured concentrations:
- from information given in publication it can be concluded that 6 concentrations were tested
- publication says: 10 daphnides in 25 mL of test water; the test used 60 daphnides
Details on test conditions:
similar to OECD 202

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
IC50
Effect conc.:
21.3 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
mobility

Any other information on results incl. tables

result reported as log1/IC50 = 3.87 mol/L

Applicant's summary and conclusion

Executive summary:

Zhao et al. (1997):

In a toxicity test similar to OECD TG 202 an IC50 of 21.3 mg/L was found for Daphnia carinata after an exposure period of 48 h. This is the most critical, valid value reported for daphnides.