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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Test procedure according to national standards. Adopted according to OECD SIDS. The original source is available and has been reviewed.

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1992
Reference Type:
secondary source
Title:
1-Chloro-2-nitrobenzene CAS: 88-73-3, SIDS Initial Assessment Report
Author:
OECD
Year:
2001
Bibliographic source:
UNEP publications

Materials and methods

Test guideline
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)
Principles of method if other than guideline:
- the test was conducted in accordance with "Bioaccumulation test of chemical substance in fish and shellfish" (Japanese Guideline by MITI, 1974)
- this guideline corresponds to OECD 305 C: Bioaccumulation: Degree of Bioconcentration in Fish (1981)
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
IUCLID4 Test substance: other TS: o-chloronitrobenzene (CAS-No. 88-73-3)
- Name of test material (as cited in study report): o-Chloronitrobenzene
- Analytical purity: no data

Sampling and analysis

Details on sampling:
- water analyzed twice a week
- fish every two weeks

Test organisms

Test organisms (species):
Cyprinus carpio
Details on test organisms:
Weight/length of exposed fish: 30g / 10cm
lipid content: 2-6%

Study design

Test type:
flow-through
Total exposure / uptake duration:
56 d

Test conditions

Test temperature:
25 °C
Nominal and measured concentrations:
test concentrations nominal: 0.025 mg/L and 0.25 mg/L

Results and discussion

Bioaccumulation factoropen allclose all
Type:
BCF
Value:
7.4 - 22.3
Remarks on result:
other: Conc.in environment / dose:0.025 mg/L
Type:
BCF
Value:
7 - 20.8
Remarks on result:
other: Conc.in environment / dose:0.25 mg/L

Any other information on results incl. tables

OECD SIDS (2001):

Measured bioconcentration factors (BCF) determined for fish (Cyprinus carpio) according to OECD guideline 305 C, were in the range of 7.0 - 22.3. 1-Chloro-2-nitrobenzene concentrations of 0.25 and 0.025 mg/L had been tested. Thus no significant potential for bioaccumulation of 1-chloro-2-nitrobenzene in aquatic organisms is indicated (MITI 1992).

Applicant's summary and conclusion