Registration Dossier
Registration Dossier
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EC number: 201-854-9 | CAS number: 88-73-3
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study. Adopted according to OECD SIDS. The original source is available and has been reviewed.
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Reference Type:
- secondary source
- Title:
- 1-Chloro-2-nitrobenzene CAS: 88-73-3, SIDS Initial Assessment Report
- Author:
- OECD
- Year:
- 2 001
- Bibliographic source:
- UNEP publications
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- (1984)
- Principles of method if other than guideline:
- Note to data access: The study report belongs to UBA (governmental agency), so it is publicly available.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1-chloro-2-nitrobenzene
- EC Number:
- 201-854-9
- EC Name:
- 1-chloro-2-nitrobenzene
- Cas Number:
- 88-73-3
- Molecular formula:
- C6H4ClNO2
- IUPAC Name:
- 1-chloro-2-nitrobenzene
- Details on test material:
- IUCLID4 Test substance: other TS: no purity given
- Name of test material (as cited in study report): 1-chlor-2-nitrobenzol
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- fish length: 2 cm
Study design
- Test type:
- flow-through
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- 23 ± 1 °C
- pH:
- pH (dilution water) 8.15 ± 0.2
- Nominal and measured concentrations:
- nominal: 0, 3.4, 6.7, 12.5, 25, 50 mg/L
measured: 0, 3.5, 6.69, 12.3, 24.9, 52.2 mg/L - Details on test conditions:
- - 14 h light / 10 h dark
- 10 fish per concentration step
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 34.8 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 34.6 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
