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EC number: 287-476-5
CAS number: 85535-84-8
In some experiments an autopsy was
performed, and no evidence for systemic toxicity reported
The dermal irritancy to 'shorn' rat skin of
various samples of C10-13 chlorinated paraffins (with extent of
chlorination varying from 41-70%) was investigated. Groups of 3 female
rats were given up to six repeated applications of various samples of
the chlorinated paraffin, either undiluted (0.1 mL) or as a concentrated
solution in a non-irritant solvent (0.1 mL). The material was applied on
alternate days under an occlusive dressing for 24 h periods, after which
time the test material was removed by washing. In some individual
experiments, an autopsy was performed to investigate signs of systemic
toxicity. No signs of systemic toxicity were reported.
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