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EC number: 287-476-5 | CAS number: 85535-84-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Long-term toxicity to fish
Administrative data
- Endpoint:
- adult fish: sub(lethal) effects
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Limited reporting in expert review; cited in final RAR (EU, 2000); considered acceptable for assessment.
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 1 975
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 2 000
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study)
- Deviations:
- yes
- Remarks:
- incomplete reporting (no data on concentrations tested, no detailed results presented, only mininmal description of test methods)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Alkanes, C10-13, chloro
- EC Number:
- 287-476-5
- EC Name:
- Alkanes, C10-13, chloro
- Cas Number:
- 85535-84-8
- IUPAC Name:
- Alkanes, C10-C13, Chloro
- Details on test material:
- - Name of test material (as cited in study report): C10-12 chlorinated paraffin
- Substance type: technical product
- Physical state: no data
- Analytical purity: no data
- Impurities (identity and concentrations): no data
- Composition of test material, percentage of components: C10-12 Chlorinated paraffin (58% chlorinated)
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
none
Sampling and analysis
- Analytical monitoring:
- not specified
- Details on sampling:
- no data
Test solutions
- Vehicle:
- not specified
- Details on test solutions:
- no data
Test organisms
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- TEST ORGANISM
- Common name: Rainbow trout
Study design
- Test type:
- flow-through
- Water media type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 20 d
- Post exposure observation period:
- no data
Test conditions
- Hardness:
- no data
- Test temperature:
- 10oC
- pH:
- no data
- Dissolved oxygen:
- no data
- Salinity:
- no data
- Nominal and measured concentrations:
- no data
- Details on test conditions:
- TEST CONCENTRATIONS
- Test concentrations: not clear from report, but appears to range between 0.04 and 100 mg/L - Reference substance (positive control):
- not specified
Results and discussion
Effect concentrations
- Duration:
- 20 d
- Dose descriptor:
- NOEC
- Effect conc.:
- < 0.04 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- behaviour
- Details on results:
- Progressive loss of motor function leading to immobility within 15-20 days
- Results with reference substance (positive control):
- no data
- Reported statistics and error estimates:
- none
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Exposure of rainbow trout (Onchorynchus mykiss) to a C10-12 chlorinated paraffin (58% chlorinated) at concentrations down to 0.04 mg/L resulted in progressive loss of motor function, and in some cases, death. The NOEC for this material was less than 0.04 mg/L. A LC50 of more than 100 mg/L after 24 days was noted.
- Executive summary:
According to an expert review, Rainbow trout (Onchorynchus mykiss) were exposed to a C10-12 chlorinated paraffin (58% chlorinated) in a flow-through system at 10oC for up to 20 days. Although not clear from the report, it appears concentrations of between 0.04 and 100 mg/L were used. A LC50 of more than 100 mg/L after 24 days was noted. Various sub-lethal effects were reported resulting in a progressive loss of motor function and immobilisation, beginning within 15 to 20 days of the start of exposure. When death occured it resulted from debilitation, cessation of feeding and other secondary effects. The NOEC for the C10-12 chlorinated paraffin was less than 0.04 mg/L in this study.
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