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EC number: 287-476-5
CAS number: 85535-84-8
In a good quality NTP study, groups of 5
male and 5 female F344/N rats were given single doses of a C12
chlorinated paraffin (60% chlorination) by stomach tube and observed for
abnormal clinical signs twice per day for up to 15 days. The chlorinated
paraffin was administered in corn oil at dose levels of 816, 1632, 3400,
6800 and 13,600 mg/kg bw.
No deaths were observed at any dose during
the study period. All animals were inactive and ataxic after dosing.
Diahrroea was seen in all males and all but the lowest dose females
lasting between 2 and 6 days.
According to EU CLP and DSD regulations,
this C12 chlorinated paraffin would not be classified as acutely toxic
by the oral route.
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