Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 939-253-5
CAS number: 68424-85-1
A study was conducted to determine the acute
oral toxicity of the test substance according to OECD Guideline 401, in
compliance with GLP. Five male and five female rats per dose group were
administered the undiluted test substance (50% purity) in a single oral
dose by gavage at the dose levels of 500, 794, 1260 and 2000 mg/kg bw.
Animals were observed 1 and 4 h after dosing and subsequently once daily
for 14 d. Mortality and evidence of overt toxicity were recorded at each
observation. Individual body weights were recorded on the day of
treatment (Day 0), Days 7 and 14, and at termination. All animals were
subjected to gross necropsy examination for any macroscopic
abnormalities. Under the study conditions, the LD50 was determined to be
795 mg/kg bw (equivalent to 397.5 mg a.i./kg bw) for male and females
combined (Jones, 1986).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again