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EC number: 939-253-5
CAS number: 68424-85-1
In a reliable guideline study, an acute 48 hour EC50 value of 0.016 mg a.i./L for freshwater invertebrates (Daphnia magna) was obtained.
An acute immobilisation guideline study using Daphnia
magna was conducted with the read-across substance C12-C16 ADBAC.
Daphnids were exposed in a static test to nominal concentrations of 0,
0.0095, 0.015, 0.024, 0.039, 0.063 and 0.1 mg/L, using two times 10
daphnids per concentration. Analytical determination was performed for
the test substance. Analytical control at the end of the exposure
demonstrated that concentration levels remained constant throughout the
exposure period. However, measured concentrations differed from 62% at
0.015 mg/L, increasing to 97 and 96% for 0.063 and 0.1mg/L.
Concentrations for the lower levels could not be analysed, as they were
below the detection limit of 7.3 µg/L. Under the conditions of the
study, 48 hour EC50of the test substance was 0.016 mg a.i./L
and the NOEC was 0.0048 mg a.i./L (Thiébaud HN,1999).
In another guideline study, the acute
toxicity of C12-C16 ADBAC to Daphnia magna under static exposure
conditions was investigated in groups of twentyDaphnia. The test
organisms were exposed for 48 hours to nominal concentrations of 0.007,
0.012, 0.019, 0.031 and 0.052 mg a.i./L. The test media were prepared in
Softened Elendt M4 medium from an aqueous stock solution with an initial
nominal concentration of 10 mg a.i./L. A control group of Daphnia was
placed in softened Elendt M4 medium alone. Analytical determination was
performed for the test substance. Observations of theDaphniawere
made after approximately 24 and 48 hours. Under the conditions of the
study, the 48 hour EC50for the immobilisation ofDaphnia
magnawas 0.016 mg a.i./L and the NOEC was 0.012 mg a.i./L (Jenkins
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