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EC number: 939-253-5
CAS number: 68424-85-1
Table 1. LC50
7-d post hatch
14-d post hatch
21 -d post hatch
28-d post hatch
Table 2. NOECs LOECs values
LOEC (µg/L) hatchability
NOEC (µg/L) hatchability
NOEC (µg/L) growth
A study was conducted to determine the
long-term toxicity to fish of the test substance according to U.S. EPA
FIFRA 72-4(a), in compliance with GLP. The experiment assessed toxicity,
mortality, hatchability and growth of Fathead minnow (Pimephales
promelas). Eggs (80 per concentration) were exposed to mean measured
concentrations of 0, 32.2, 75.9, 134.2, 186.8, 273.2 and 488.7 µg a.i./L
of radiolabelled test substance. Analytical determination was performed
and the sample concentrations were verified by liquid scintillation
counting. After 7 days, surviving fry from two replicates were thinned
to 10 animals per replicate for each exposure group (total of 20 animals
per concentration) and exposed to the same concentrations for a 28 day
post-hatch static renewal toxicity test. Observations of symptoms and
mortality were conducted daily. Under the study conditions, the 28 d
NOEC for hatchability was 273.7 µg/L, the 28 d NOEC for survival was
32.2 µg a.i./L and the 28 d NOEC for growth was > 32.2 µg a.i./L
28 d NOEC for Fathead
minno wmortality due to the test substance was determined
to be 0.032 mg a.i./L (measured).
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