Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 939-253-5
CAS number: 68424-85-1
A study was conducted to determine the in
vivo toxicity of the test substance, C12-16 ADBAC (80.2% active in
ethanol) according to OECD Guideline 474, in compliance with GLP. This
study was performed to evaluate the chromosome-damaging effect of the
test substance in mice. The experimental animals were 50 NMRI mice,
divided into 5 groups. Of the 5 groups, three were test groups, one
negative control group and one positive control group. The test groups
were treated with 400 mg test substance/kg bw, the negative control
group with distilled water and the positive control group with 30 mg
cyclophosphamide/kg bw. The mice were killed 24, 48 and 72 h,
respectively after treatment. From bone marrow smears micronucleus
counts were made per 1000 polychromatic erythrocytes. Under the test
conditions, the test substance did not induce an increase in the
frequency of micronucleated polychromatic erythrocytes in peripheral
blood samples from both male and female mice (Kallesen, 1985).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Tällä verkkosivustolla käytetään evästeitä parhaan mahdollisen käyttäjäkokemuksen varmistamiseksi.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again