Registration Dossier

Administrative data

Hazard for aquatic organisms

Hazard for air

Hazard for terrestrial organisms

Hazard for predators

Additional information

Conclusion on classification

(1) The proposed classification (Environment) according to 67/548/EC would be as follows:

(a) Basis for classification:

Acute toxicity to fish: LC50 (96 h)= 27.7 mg/L, based on measured concentrations (CITI, 1997).     R52

Acute toxicity to Daphnia: EC50 (48 h) = 6.77 mg/L (CITI, 1997).                                                        R51

Acute toxicity to algae: EbC50 (0 -72 h) = 19.5 mg/L (measured concentration)                                   R52

Biodegradation: not readily biodegradable                                                                                           

log Pow: 3.42, i.e ≥ 3.0 (but BCF 3.9 -8.1, i.e. ≤ 100; therefore not R53!))

(b) Classification (67/548/EC, No. 5.2.1.1)

N, R51 Toxic to aquatic organisms.

(c) Classification (1272/2008/EC, No. 4.1)

Aquatox chronic 2; H411

(2) Examination, whether PBT or vPvB apply

criterion

result

         justification

reference

PBT

persistence

+ / -

inadequate data

bioaccumulation

No

BCF 2000

NITE (2002; RL 2)

Toxic

(a)           Long term aquatic NOECs

(b)           CMR

(c)           T (or Xn), R48 according to 67/548 EC

No

No

+ / -

 (a1) fish: NOEC >0.01 mg/L

(a2) aqu. invertebrates: NOEC >0.01 mg/L

C: no data

M: negative

R: negative

inadequate data:

(1)    Japanese language;

(2)   Short-term study: pregnant females

(3)   no subchronic study available.

CITI (1997; RL4)

CITI (1997; RL4)

No data

MHLW (1997, RL2)

MHLW (1997, RL2)

MHLW (1997, RL2)

Overall result PBT: No

vPvB

persistence

+ / -

inadequate data

bioaccumulation

No

BCF 5000

NITE (2002; RL 2)

Overall result vPvB

No