Registration Dossier

Ecotoxicological information

Toxicity to other above-ground organisms

Administrative data

Endpoint:
toxicity to other above-ground organisms
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable, well-documented publication which meets basic scientific principles

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1987
Report Date:
1987

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Exposure of larvae for 48 hours
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Purity: analytical grade

Sampling and analysis

Analytical monitoring:
not specified

Test substrate

Vehicle:
no

Test organisms

Test organisms (species):
other: xenopus laevis

Study design

Study type:
laboratory study
Limit test:
no
Total exposure duration:
48 h

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
LD50
Effect conc.:
13.5 other: mg/L
Conc. based on:
test mat.
Basis for effect:
mortality

Applicant's summary and conclusion

Conclusions:
The LC50 (48 h) of 3, 5, 5-trimethylhexan-1-ol to larvae of Xenopus laevis was 13.5 mg/L
Executive summary:

The LC50 (48 h) of 3, 5, 5-trimethylhexan-1-ol to larvae of Xenopus laevis was 13.5 mg/L. The sensitivity of this species was reportedly comparable to that of fish (De Zwart and Slooff, 1987).