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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

Based on a growth inhibition study with the protozoan, Entosiphon sulcatum, the 72-hour toxicity threshold for epichlorohydrin is 35 mg/L. 

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
35 mg/L

Additional information

Two microorganism studies were examined for epichlorohydrin and both were deemed reliable and useful for risk assessment. One study examined growth inhibition in the protozoan, Entosiphon sulcatum,over a 72 hour exposure period, while the other study measured growth inhibition of the bacteria, Pseudomonas putida,over a 16-hour exposure period. The growth inhibition test with E. sulcatum reported a toxicity threshold value of 35 mg/L epichlorohydrin. The growth inhibition study with P. putida reported a 16-hour toxicity threshold value of 55 mg/L epichlorohydrin. The value of 35 mg/L was selected as the key parameter for this endpoint, since this was the lowest toxicity value reported for microorganisms.