Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 203-439-8 | CAS number: 106-89-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- Epichlorohydrin
- Type of composition:
- boundary composition of the substance
- State / form:
- liquid
- Reference substance:
- Epichlorohydrin
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The data show that the properties of the substance do not meet all the specific criteria detailed in Annex XIII or do not allow a direct comparison with all the criteria in Annex XIII but nevertheless indicate that the substance would not have all these properties and the substance is not considered a PBT/vPvB.
Constituent
P/vP
B/vB
T
Epichlorohydrin
(main constituent)t½, hydrolysis≤ 7.3 d;
Product from hydrolysis is readily biodegradable.log Pow= 0.45
Product from hydrolysis is metabolized and excreted in mammals.NOECAlgae= 1.7 mg/L
EC50acute aquatic≥ 10.7 mg/L
Carcinogen Cat. 2
Not classified as mutagen, repro toxicant, T-R48 nor Xn-R48.t½,< 40 d
Not P based on REACH Annex XIII.Log Pow< 4.5
Likely not B based on screening criteria.Carcinogen Cat. 2
T based on REACH Annex XIII.
Reference
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