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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

The 48-hour EC50 value of 23.9 mg/L for epichlorohydrin is the geometric mean calculated from three 48-hour EC50 values reported in a valid exposure study with Daphnia magna.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
23.9 mg/L

Additional information

One acute toxicity test with Daphnia magna was assessed for this endpoint. This study was deemed of good quality and useful for risk assessment (Klimish score = 2). In this study, a series of three acute exposures with epichlorohydrin were conducted with D. magna and three 48-hour EC50 values (based on immobility) were calculated. The calculated EC50 values were 28.9, 22.6 and 21.0 mg/L epichlorohydrin. The geometric mean of the three values was 23.9 mg/L epichlorohydrin, and this value was selected as the key parameter for this endpoint.