Registration Dossier

Environmental fate & pathways

Hydrolysis

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Epichlorohydrin is susceptible to hydrolysis which will likely lead to 3-chloro-1,2,propanediol with a pseudo first order reaction half-life of 4 days at pH 7 and 20°C. 

Key value for chemical safety assessment

Additional information

Epichlorohydrin is susceptible to hydrolysis which will likely lead to 3-chloro-1,2,propanediol, however no analytical work on the breakdown product was presented in the report. The half-life for this reaction has been determined in an OECD 111 study at three different pH values with half-lives ranging from 4 to 7 days at 20 °C. Similar half-lives were reported in another study (2.5–3.3 days). The half-life at neutral pH is anticipated to be lower compared to alkaline or acidic conditions, the first study cited reports slightly shorter half-lives at pH=7.

Epichlorohydrin will also react with other nucleophiles commonly present in waste water or natural waters (Thiols, Phenols, Alcohols).