Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

Description of key information

waiver, see Discussion

Key value for chemical safety assessment

Additional information

In accordance with Column 2 of Annex IX, the study does not need to be conducted if it is scientifically not possible to perform the test. In the case of epichlorohydrin (as well as other epoxides), the pKa for protonation of the epoxy ether atom is approximately -2 (as cited in "Brown WH, Foote CS, Iverson BL, Anslyn E (2009).Organic Chemistry, 5th Edition. 11: Ethers, Sulfids, and Epoxides. Brooks/Cole Publishers,,,), and thus cannot be measured under dilute aqueous solution conditions (pH ranging from 0-14), and is not relevant to pH encountered under environmental or physiological conditions