Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Toxicity to terrestrial arthropods:

Study was conducted to determine the effect of test chemical on the larvicidal activity of Ochlerotatus caspius. Chemical was analytically monitored by GC. 1 ml DMSO use as a solvent in which 200 ml sea water were added. Testes at 4 different concentrations (5-30 ul/200 ml sea water). Larvae collected from salty rocky pools, from the shore of Enfe, Batroun Co., Lebanon. Mortality were observed in the interval of 24 hrs. In which 3 replicates were used and in each larval tray 15 test organism added. Test conducted for 48 hrs for determining the effect of chemical on the larvicidal activity of Ochlerotatus caspius (Mosquito). Based on the mortality of test organism for 48 hrs and 24hrs, the LC50 was determine to be 33.31 and 33.65 mg/l. and the LC90 was determine at 47.91 mg/l at 48 hrs and 50.85 mg/l after 24 hrs.

Additional information

Toxicity to terrestrial arthropods:

Summarized result for the toxicity of chemical on the growth of terrestrial arthropods are as follows:

 

In the first key study for target chemical from peer reviewed journal toxicity was measured. Study was conducted to determine the effect of test chemical on the larvicidal activity of Ochlerotatus caspius. Chemical was analytically monitored by GC. 1 ml DMSO use as a solvent in which 200 ml sea water were added. Testes at 4 different concentrations (5-30 ul/200 ml sea water). Larvae collected from salty rocky pools, from the shore of Enfe, Batroun Co., Lebanon. Mortality were observed in the interval of 24 hrs. In which 3 replicates were used and in each larval tray 15 test organism added. Test conducted for 48 hrs for determining the effect of chemical on the larvicidal activity of Ochlerotatus caspius (Mosquito). Based on the mortality of test organism for 48 hrs and 24hrs, the LC50 was determine to be 33.31 and 33.65 mg/l. and the LC90 was determine at 47.91 mg/l at 48 hrs and 50.85 mg/l after 24 hrs.

 

Similarly the second study was also supports the nature of chemical from secondary source 2018. Study was conducted to determine the toxicity of chemical on Aedes aegypti. Test performed for 24 hrs on the 3-4 ins larval Aedes aegypti (Yellow Fever Mosquito). Based on the mortality of test organism Aedes aegypti (Yellow Fever Mosquito), by the chemical Thymol (5-Methyl-2-(1-methylethyl)phenol) exposure for 24 hrs, the LC50 was determine to be 79 mg/l. As the chemical was readily biodegradable in water thus consider as nontoxic and not classified as per the CLP classification criteria.