Registration Dossier
Registration Dossier
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EC number: 201-944-8 | CAS number: 89-83-8
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- not specified
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: safe use as food addidive
Data source
Reference
- Reference Type:
- publication
- Title:
- No information
- Author:
- Federal Register, Vol.68, No 109/Friday, June 6, 2003/Rules and Regulations
- Year:
- 2 003
- Bibliographic source:
- Federal Register, Vol.68, No 109/Friday, June 6, 2003/Rules and Regulations
Materials and methods
- Type of study / information:
- Type of experience: Human - Exposure through Food
- Endpoint addressed:
- not applicable
- Principles of method if other than guideline:
- safe use of tyol in food additives
- GLP compliance:
- no
Test material
- Reference substance name:
- Thymol
- EC Number:
- 201-944-8
- EC Name:
- Thymol
- Cas Number:
- 89-83-8
- Molecular formula:
- C10H14O
- IUPAC Name:
- 5-methyl-2-(propan-2-yl)phenol
- Details on test material:
- no data
Constituent 1
Method
- Details on study design:
- no data
Results and discussion
- Results:
- see: Any other information on results incl. tables
Any other information on results incl. tables
Thymol is found naturally occuring in thyme herb. Thyme is used as a food seasoning ingredient, and is generally recognized as a safe natural seasoning by FDA. Thyme oil also is recognized as a GRAS essential oil by FDA. Thymol may safely used in food as as a synthetic flavoring substance when used in the minimum quantity to produce the intended effect. Levels of thymol reported in foods where it is permitted as a direct food additive have been stated as 44 ppm in ice cream, ices, etc., 2.5 ppm to 11 ppm in non-alcoholic beverages; 9.4 ppm in candy, 5ppm to 6.5 ppm in baked goods, and 100 ppm in chewing gum.
Applicant's summary and conclusion
- Executive summary:
- Thymol is found naturally occuring in thyme herb. Thyme is used as a food seasoning ingredient, and is generally recognized as a safe naturalseasoning by FDA. Thyme oil also is recognized as a GRAS essential oil byFDA. Thymol may safely used in food as as a synthetic flavoring substance when used in the minimum quantity to produce the intended effect. Levelsof thymol reported in foods where it is permitted as a direct food additivehave been stated as 44 ppm in ice cream, ices, etc., 2.5 ppm to 11 ppmin non-alcoholic beverages; 9.4 ppm in candy, 5ppm to 6.5 ppm in bakedgoods, and 100 ppm in chewing gum.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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