Registration Dossier
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EC number: 201-245-8 | CAS number: 80-05-7 Bisphenol A; BPA
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
No effects on mortality or number of juveniles were observed in a 28-day potworm (Enchytraeus crypticus) reproduction study (Moser and Egeler, 2007a; Staples et al., 2010). A NOEC of 100 mg/kg dw was determined.
Key value for chemical safety assessment
- Long-term EC10, LC10 or NOEC for soil macroorganisms:
- 100 mg/kg soil dw
Additional information
In addition to performing a chronic study with earthworms, Johnson et al. (2005a) performed a short-term, acute study. However, the acute study is considered unreliable for a number of reasons, including that the control survival did not meet the validity criteria and there were no effects in the chronic study at doses that caused mortality in the acute study. The inconsistency in results prompted a new, fully valid chronic study with the potworm Enchytraeus crypticus (Moser and Egeler, 2007a). Final concentrations of Bisphenol A in the test systems, consisting of artificial soil, were 1.0, 9.5, 17.1, 30.9, 55.6, and 100 mg test item/kg soil dw (dry weight). No effects on mortality or number of juveniles were observed at the highest dose tested of 100 mg/kg dw. This is in agreement with the findings from the earthworm chronic study (Johnson et al., 2005) where the NOEC of 100 mg/kg was also established.
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