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EC number: 200-756-3
CAS number: 71-55-6
1,1,1 -trichloroethane displays
similar moderate acute toxicity to marine and freshwater species of
fish, invertebrates and algae. A limited number of chronic studies are
available for fish and invertebrates. The applicant believes that there
are sufficient studies available of acceptable quality to permit a valid
risk assessment to be conducted. The Kaw (air/water partition
coefficient) is very low therefore it is essential to conduct all
toxicity assessments in closed vessels preferably with analytical
determination of the concentration tested. The information available has
been reviewed by several authors (euro Chlor, 1999) who conclude that
the type of toxicity expressed by 1,1,1-trichloroethane is basic rather
than specific (there is no definitive mode of action) and it is
therefore possible to use studies conducted in either the freshwater or
marine environment for risk assessment for both environments. In
addition they are also of the opinion that there are sufficient good
studies available to permit a valid risk assessment. Only the algae key
study (Brack and Rottler 1994) departed from the bulk of data. As it has
also been observed on several other substances tested in this paper a
new study has recently been commissioned and results available (Gancet,
2011) for updating the registration dossier. The 3 trophic levels used
for classification and risk assessment have data that can be summarised
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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