Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-756-3 | CAS number: 71-55-6
Endpoint summary
Administrative data
Description of key information
Additional information
1,1,1 -trichloroethane displays similar moderate acute toxicity to marine and freshwater species of fish, invertebrates and algae. A limited number of chronic studies are available for fish and invertebrates. The applicant believes that there are sufficient studies available of acceptable quality to permit a valid risk assessment to be conducted. The Kaw (air/water partition coefficient) is very low therefore it is essential to conduct all toxicity assessments in closed vessels preferably with analytical determination of the concentration tested. The information available has been reviewed by several authors (euro Chlor, 1999) who conclude that the type of toxicity expressed by 1,1,1-trichloroethane is basic rather than specific (there is no definitive mode of action) and it is therefore possible to use studies conducted in either the freshwater or marine environment for risk assessment for both environments. In addition they are also of the opinion that there are sufficient good studies available to permit a valid risk assessment. Only the algae key study (Brack and Rottler 1994) departed from the bulk of data. As it has also been observed on several other substances tested in this paper a new study has recently been commissioned and results available (Gancet, 2011) for updating the registration dossier. The 3 trophic levels used for classification and risk assessment have data that can be summarised as follows:
| Acute E(L)C50 (mg/l) | Chronic NOEC (mg/l) | |
| Alga | 41 | 1,3 |
| Invertebrate | 42,3 | 7,7 |
| Fish | 57,6 | 7,5 |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
