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EC number: 200-756-3
CAS number: 71-55-6
The results of the number of studies have been included in this section. However from a risk assessment standpoint (De Rooij et al 2004) the most useful document is a review conducted by EURO CHLOR for the European Union Commission conducted to assist in the formulation of policy on chlorinated industrial chemicals. The results of this review showed that although the bulk of the trichloroethane released into the environment would find its way into the atmosphere sufficient would be present in surface waters (marine and freshwater) to justify a full-scale risk assessment. The studies available in this review were sufficient to conclude that the risk to the aquatic environment based on figures obtained before the effects of the Montreal protocol came into effect were sufficient to indicate that for fish there was no cause for concern.
The results of a risk assessment (De
Rooij et al 2004) on a
review conducted by EURO CHLOR indicate that there appeared to be no
difference between toxicity to fresh water and marine fish and, as
trichloroethane is considered to be a basic rather than a specific
toxin, the results from both of freshwater and marine species can be
used together. Results of the review are as follows.
studies on freshwater fish.
SF 1000 (ug/L)
Loss of equilibrium
et al 1978
Respiration, loss of equilibrium
et al 1985
et al 1981
US EPA 1980
Leuciscus idus melanotus
Juhnke & Ludeman 1978
studies on marine fish.
No isomer confirmation
Pearson & McConnel 1975
Heitmuller et al 1981
Analysis A = Yes, N =
Study type S = static,
SS = semi-static, FT = flow through. C = closed system.
Rating for validity 1
= valid without restriction, 2 = valid with restrictions, 3 = invalid, 4
= not assignable (inadequate data).
addition to the studies listed above other studies are included in the
dossier but they do not materially change the results obtained in the
published risk assessment (quality criteria for all additional studies
are below the reviewers criteria of category 1 - valid without
The results from acute studies
which the authors considered to be valid without restriction (category
1) show that the 96h LC50 and EC50 NOEC) values for fish are 42.3 and
11.1mg/L. Based on that these results and the monitored results of
concentrations of 1,1,1-trichloroethane in river and estuarine
situations in northern Europe the authors conclude that the PEC/PNEC
ratios incorporating standard safety factors are comfortably below (35x)
levels that would cause concern
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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