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EC number: 200-756-3
CAS number: 71-55-6
Table 1: Erythmea scores following
topical challenge with 50 % (w/w) 1,1,1-trichloroethane
S=dryness of the
0 - no visible
1 - discrete or
2 - moderate and
3 - intense
The delayed contact hypersensivity of TRICHLOROETHANE-1.1.1
NOT STABILIZED was evaluated in Guinea pigs according to OECD
N°406 guideline (Magnusson and Kligman test).
The induction phase has been realized both
by intradermal route on day 1 (10% in corn oil) and by cutaneous route
on day 8 (undiluted) in 2 groups of guinea pigs: 5 males and 5 females
for control group and 10 males and 10 females for treated group. The
challenge phase was realized on day 22 by cutaneous application of 50 %
(w/w)on the right (acetone on the left); the cutaneous reactions were
scored 24 and 48 hours after the challenge phase.
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