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EC number: 200-756-3
CAS number: 71-55-6
a study conducted under the auspices of the US EPA looked at the effect of 1,1,1-trichloroethane and other materials of national interest on the biological degradation of the sewage in pseudo commercial treatment plants. The results of this study showed that the EC50 for trichloroethane was 360mg/L.
The UK1996 review considers that
bacteria are the most sensitive organisms to 1,1,1-trichloroethane and
reviews the data on single and mixed species. The results of this review
are to say the least confusing as they do not entirely agree with the
published studies reported in the biodegradation section of this
dossier. It is acknowledged that individual species of bacteria differ
in the sensitivity to 1,1,1-trichloroethane. It has already been
adequately demonstrated that the degradation of 1,1,1-trichloroethane
only takes place under anaerobic conditions and that any studies
conducted other than in sealed vessels must be considered unreliable. It
is also acknowledged that 1,1,1-trichloroethane possesses only basic
activity rather than specific activity against bacteria. In practice the
most important requirement, after taking into account the fact that this
material does not naturally occur in the environment, of the potential
adverse effects relating to release is to determine at what
contamination level effects on sewage treatment will occur. It is for
this reason that the American study has been selected as the key study
as it is conducted to a recognise guideline ( with modification to
reduced volatilisation) namely OECD209 and meets the basic quality
criteria set for this guideline. It should be noted that this study was
not considered by the UK government reviewers which in the opinion of
the applicant is surprising.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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