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EC number: 228-408-6
CAS number: 6259-76-3
The irritation potential of hexyl salicylate was tested in a study by
Haynes (1986), after exposure for 4 hours under semi-occlusive
conditions in the rabbit, both as 100% and as 50% in DEP. The mean score
for erythema over the 24-72 hour period was 2.0 for the 100% pure
substance. The mean score for oedema over the 24-72 hour period was 2.16
for the 100% pure substance. Hexyl salicylate was found to be a moderate
skin irritant under the conditions of this study. The mean scores for
skin irritation do not trigger classification as a skin irritant;
however as the reactions were not reversible within the study period,
classification is appropriate.
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