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Classification & Labelling & PBT assessment

PBT assessment

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PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB
Justification:

Persistence

Hexyl salicylate is readily biodegradable and therefore has no potential to persist.

Bioaccumulation

Using the logKow figure determined by Rudio (1996) of 5.5, a BCF was derived using the equation described in the Handbook of Chemical Property Estimation Methods.The Log BCF was estimated to be 3.95 (BCF = 8913).

Due to the readily biodegradable nature of hexyl salicylate, Rudio (1995), exposure to the aquatic environment will be limited. Its readily biodegradable nature will also mean that the BCF will be lower than that estimated from the Log Kow as the substance is expected to be metabolised by aquatic organisms.

Further calculations were performed using the BCFBAF model within the EPA's Epiweb program. This uses a slightly different formula to estimate BCF to that described in the handbook of calculations resulting in an estimated BCF of 1977. In addition to this, the model estimates the biotransformation half-life as 0.24 days and uses this to refine the BCF estimates. These additional calculations estimate Log BCF in the range 1.99 to 2.17 (BCF = 98 to 148).

 

Toxicity

On the basis of the hazard assessment, hexyl salicylate is not expected to be carcinogenic, mutagenic or a reproductive toxicant and is not classified as T, R48, or Xn, R48 according to Directive 67/548/EEC.