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EC number: 228-408-6 | CAS number: 6259-76-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The purpose of this study was to evaluate the acute toxicity of hexyl salicylate to Daphnia magna in a 48 hour, semi-static study with renewal of the test media after 24 hours. This study was carried out to OECD Guideline 202. Nominal exposure concentrations were 0 (control), 0 (solvent control), 0.05, 0.1, 0.23, 0.5 and 1.0 mg/L, the corresponding mean measured concentrations were 0.03, 0.072, 0.140, 0.310 and 0.726 mg/L. The results of the study are based on the mean measured exposure concentrations.
The 48 hour EC50 was calculated to be 0.357 mg/L (with 95% confidence limits of 0.228 to 0.871 mg/L), the corresponding no-observed effect concentration was 0.140 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.357 mg/L
Additional information
The purpose of this study (Pavic and Wydra, 2008), was to evaluate the influence of the test item N-hexylsalicylate on the immobilisation of Daphnia magna. The 48-hour EC50 value was 0.357 mg test item/L.
Based on the results of the acute toxicity to Daphnia study, Hexyl salicylate is classified as N Dangerous for the environment with the risk phrase 'R50- very toxic to aquatic organisms' according to Directive 67/548/EEC.
Hexyl salicylate is classified as an acute category 1 with the signal word 'Warning' and the hazard statement 'H400 Very toxic to aquatic life' in accordance with Regulation (EC) No. 1272/2008.
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