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EC number: 228-408-6
CAS number: 6259-76-3
No data are available for the toxicity to microorganisms of hexyl salicylate.
No data has been generated to fulfil this data requirement. However, a
biodegradation study with hexyl salicylate was conducted according to
OECD guideline 301F with a nominal concentration of 100 mg/L. Under the
conditions of the test, hexyl salicylate underwent 91 % biodegradation
after 28 days. Biodegradation reached 82 % at the end of the 10-day
window (days 2 to 12).
Thus, hexyl salicylate should be regarded as readily biodegradable
according to this test.
At the concentration used in the test (100 mg/L), hexyl salicylate is
not inhibitory to the micro-organisms.
In the absence of toxicity study conducted according to OECD guideline
209 the ECHA guidance document, Chapter R220.127.116.11 states the
following: “The assumption that the substance under investigation is not
inhibitory to the micro-organisms when dosed in the test system is
implicit in ready biodegradability testing (i.e. ... OECD 301F). If a
compound degrades well in a ready biodegradability test, or does not
inhibit the degradation of a positive control at a certain
concentration, this concentration can be used as a NOEC value”.
Therefore it is considered appropriate to set the NOEC for this endpoint
as 100 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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