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EC number: 228-408-6
CAS number: 6259-76-3
No additional information
In the study conducted by Gage (1974), the test substance, methyl
salicylate, was examined for its ability to induce toxicity following
repeated exposure for a period of 20 days. Female rats were exposed for
7 hours daily via whole body inhalation chamber to 700mg/m3 (120ppm),
for a period of 20 days. Observations included conditions and
behaviour, body weight, haematology, urinalysis, gross pathology and
No toxic signs were observed throughout the duration of the study and at
autopsy, organs appeared normal. Under the conditions of this study,
the no observed adverse effect level (NOAEL) was 120ppm via inhalation
or circa 700mg/m3.
Due to the similar structural, physical and chemical properties of
methyl salicylate, it was considered appropriate for the purposes of
read across to hexyl salicylate
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