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EC number: 228-408-6
CAS number: 6259-76-3
No additional information
Hexyl salicylate was investigated for its ability to induce eye
irritation. The test substance was applied undiluted to the left eye of
each of 4 female SPF albino rabbits in a volume of 0.1ml. The right eye
of each animal served as the untreated control. The eyes were examined
and the changes graded according to a numerical scale at one, 24, 48 and
72 hours after dosing. The cornea, iris and conjunctivae were examined
and scored based on their reactions to the test material. Slight to
well-defined signs of irritation were observed in the treated eyes at
the 1, 24 and 48 hour examination time-points. However, all effects were
fully reversible and no signs of irritation were observed after 72
hours. Under the conditions of this study hexyl salicylate does not
induce irritation of the eyes following its application. Based on these
results, it does not need to be classified according to Regulation EC
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