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Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary literature

Data source

Reference
Reference Type:
publication
Title:
Report to RIFM, February 16, 1973
Author:
Opdyke DLJ
Year:
1976
Bibliographic source:
Levenstein I; Report to RIFM, February 16, 1973: cited in Opdyke, D.L.J.: Fd Cosmet. Toxicol. 14, 473-474 (1976)

Materials and methods

Principles of method if other than guideline:
acute dermal toxicity was tested
GLP compliance:
not specified
Test type:
other: no data

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Duration of exposure:
no data
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw

Any other information on results incl. tables

no data

Applicant's summary and conclusion

Executive summary:

In rabbits the acute dermal LD50 exceeded 5000 mg/kg bw