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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Reference
Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1985
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Qualifier:
according to
Guideline:
OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)
GLP compliance:
not specified
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: AJ01
Radiolabelling:
no
Test organisms (species):
Cyprinus carpio
Details on test organisms:
Lipid content in % : 4.7
Route of exposure:
aqueous
Test type:
flow-through
Water / sediment media type:
natural water: freshwater
Total exposure / uptake duration:
6 wk
Test temperature:
25 +- 2 °C
Dissolved oxygen:
6-8 mg/L
Nominal and measured concentrations:
nominal: 200 µg/L and 20 µg/L

Lipid content:
4.7 %
Time point:
end of exposure
Key result
Type:
BCF
Value:
>= 0.5 - <= 15 dimensionless
Calculation basis:
steady state
Remarks on result:
other: Conc.in environment / dose:200 µg/L
Type:
BCF
Value:
>= 4.6 - <= 11 dimensionless
Calculation basis:
steady state
Remarks on result:
other: Conc.in environment / dose:20 µg/L
Validity criteria fulfilled:
not specified
Conclusions:
The bioconcentration factor ranges from <0.5 - 15 at 0.2 mg/L and <4.6-11 at 0.02 mg/L test concentration using Cyprinus carpio as test organism.
Executive summary:

In a bioaccumulation study, corresponding to OECD Guideline 305C, a BCF of <0.5 - 15 at 0.2 mg/L test concentration and <4.6 - 11 at 0.02 mg/L test concentration for DL-Menthol was determined with Cyprinus carpio as test organism (15-20 animals/concentration) within 6 weeks.

Description of key information

In a bioaccumulation study, corresponding to OECD Guideline 305C, a BCF of <0.5 - 15 at 0.2 mg/L test concentration and <4.6 - 11 at 0.02 mg/L test concentration for menthol was determined with Cyprinus carpio as test organism (15 - 20 animals/concentration) within 6 weeks.

Key value for chemical safety assessment

BCF (aquatic species):
15 dimensionless

Additional information