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EC number: 239-622-4
CAS number: 15571-58-1
An OECD Guideline 416
(Two-Generation Reproduction Toxicity Study) was carried out with the
mixture Dioctyltin bis(IOMA) [CAS No. 26401-97-8]:Octyltin tris(IOMA)
[CAS No. 26401-86-5] (78.8:16.9% mixture); Rats were exposed to 20, 60
and 200 ppm in the diet . An untreated control group was tested
concurently. Various general toxicological parameters were studied as
well as reproductive/developmental observations of parent animals and
Under the experimental
conditions, the NOAEL for the F0 parental generation was 20 ppm (~1.5
mg/kg bw/d), based on a reduction in the relative thymus weight of males
at 60 ppm. No substance-related pathological findings were observed.
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