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Toxicity to microorganisms

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Description of key information

The 3 hour EC50 for DOTE for inhibiting the respiration of aerobic wastewater bacteria has been determined to be > 100 mg/L.

Key value for chemical safety assessment

EC50 for microorganisms:
100 mg/L

Additional information

DOTE inhibitory potential toward the respiration of aerobic wastewater bacteria has been investigated by Baumann (1992). Activated sludge from a sewage treatment plant was exposed for 3 hours following the procedure described in guideline: 87/302/EEC page 118-122 Activated sludge respiration inhibition test.

Study generally followed guideline, and met validity criteria. However, due to the insolubility of the test substance in the test medium, a constant factor between the test concentrations could not be achieved. It was not possible to determine an absolute EC50 (result is >= 100 mg/L) given that no inhibition was observed over the concentrations tested

The results were calculated based on nominal concentrations:

EC50(3h) = > 100 mg/l

EC20(3h) = > 100 mg/l

EC80(3h) = > 100 mg/l