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EC number: 239-622-4
CAS number: 15571-58-1
A repeated dose oral toxicity study was
carried out with rats and a mixture of Dioctyltin bis(2-EHMA) [CAS No.
15571-58-1]:Octyltin tris(2-EHMA) [CAS No. 27107-89-7]: Trioctyltin
(2-EHMA) [CAS No. 61912-55-8] (97.0:0.3:2.17% mixture). The study
predates GLP, but is well documented and quality assurance is
comparable. No information on the homogeneity or stability of the test
substance in the diet was provided, due to which the study was
considered less reliable. The NOAEL was determined to be 10 ppm
(equivalent to 0.5 mg/kg bw/day) and the LOAEL was determined to be 25
ppm (equivalent to 1.3 mg/kg bw/day) based on reduced thymus weight.
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