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EC number: 214-703-7 | CAS number: 1187-93-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no data: aquatic toxicity unlikely
Marine water
- Hazard assessment conclusion:
- no data: aquatic toxicity unlikely
STP
- Hazard assessment conclusion:
- no emission to STP expected
Sediment (freshwater)
- Hazard assessment conclusion:
- no exposure of sediment expected
Sediment (marine water)
- Hazard assessment conclusion:
- no exposure of sediment expected
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no exposure of soil expected
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
PMVE is a volatile gas at ambient conditions with a boiling point in the range of -26 °C (Yaws, Carl L. ©2010 Knovel), in addition, in case of accidental emission, it is released only to air compartment as indicated from the EQC Fugacity III Model (v.1.0, The Canadian Centre for Environmental Modelling and Chemistry, May 2003). Moreover on the basis of its Henry's Law constant of 32,100 P m^3/mol (HENRYWIN v3.20, EPISUITE v1.00) that entails a not measurable vapour pressure (i. e. 10^5 Pa) and a limited solubility in water (the value of water solubility of 31.5 mg/l has been evaluated in a closed system with the atmosphere saturated of PMVE hence it represents an overestimation of the actual water solubility of PMVE in the natural system) PMVE is expected to primarily and rapidly partition to the atmosphere.
Hence, due to the gaseous nature of the substance, its partition to the atmosphere, its limited water solubility as well as the consequent difficulty to appropriately test PMVE and provide meaningful results, no experimental aquatic toxicity data are reported, consequentely PNECs for aquatic organisms have not been calculated.
PNECs for sediment (freshwater or marine) and soil can't be derived and are technically not feasible, as PMVE is expected to primarly and rapidly partition to the atmosphere as also discussed above.
PNEC for air are not calculated since PMVE is not considered to represent an hazard.
It has been shown that the atmospheric degradation of PMVE produces the same fluorinated radical species as formed during the degradation of HFCs. HFCs do not impact stratospheric ozone and the same conclusion applies to HFEs; PMVE has an ozone depletion potential of zero. A rate constant of k(OH + CF3OCFCF2) = (2.6 +/- 0.3) x 10^-12 cm3 molecule^-1 s^-1 at 296 K in 700 Torr of air and an atmospheric lifetime of CF3OCF=CF2 with respect to reaction with OH of 0.023 years (8 days) have been estimated. The global warming potential (GWP) was estimated using the radiative forcing, lifetime and molecular weight to be 1.20 x 10^-3 for a 20 year horizon and ca. 4.57 x 10^-4 for a 100 year time horizon. Hence the GWP of PMVE can be considered negligible (Mashino, M., 2000) (Mashino, M., 2000).
According to Zhuangjie et al, the atmospheric lifetime of PMVE is then estimated to be less than 5 days due to the OH attack, in addition the Global Warming Potential for the PMVE is predicted to be small (less than 0.01) due to the short atmospheric lifetime of this molecule. On the basis this it is not expect the use of PMVE to lead to any significant impact on climate (Li, Zhuangjie et al. 2000).
Conclusion on classification
Since PMVE is a gas at ambient conditions (used in sealed systems) and its water solubility is limited, it does not represent a hazard to aquatic life. For this reason, no aquatic toxicity testing has been conducted. ECOSAR predictions for aquatic toxicity are applied, however the ECOSAR results have not been considered in this assessment since the ECOSAR model cannot be considered reliable for this class of chemicals. It can be concluded that PMVE does not pose a toxicity risk to aquatic or terrestric organisms in the unlikely event of entering and remaining in these compartments water or soil long enough to potentially affect organisms at all.
Based on the above considerations the substance is neither classifiable for acute nor chronic aquatic toxicity according to CLP (EC No 1272/2008)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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