Registration Dossier

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Long -term aquatic toxicity testing is not proposed by the registrant as the chemical assessment does not indicate a need to investigate further effects on aquatic organisms. This is based on the knowledge that the aquatic toxicity properties of the substance is unlikely as the substance is a volatile gas which is expected to rapidly partition to atmosphere and it is not expected to partition into water, in fact:
The Guidance on Information Requirements and Chemical Safety Assessment Chapter R.7a: Endpoint Specific Guidance, Appendix R.7.1-4 indicates that substances with a Henry's Law constant of around 1 hPa m3/mole will rapidly volatilise from water. On the basis of its boiling point of -26 °C (Yaws, Carl L. ©2010 Knovel) that entails a not measurable vapour pressure (i. e. 10^5 Pa) and a limited water solubility (the water solubility value of 31.5 mg/l has been evaluated in a closed system and with the atmosphere saturated of PMVE hence it represents an overestimation of the actual water solubility of PMVE in the natural system) PMVE is expected to primarily and rapidly partition to the atmosphere.
The EQC Fugacity III Model confirms that the whole amount of PMVE released to air remains in this compartment. The model was run assuming emission only to air. In case of an accidental emission, PMVE is only released to air, because PMVE is a volatile gas at ambient conditions with a boiling point of -26 °C. Therefore, PMVE would not be expected to partition into water.

Key value for chemical safety assessment

Additional information

Categories Display