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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

In accordance with section 1 of REACH (Regulation (EC) No 1907/2006) Annex XI the bioaccumulation study required in section 9.3.2 Annex IX of REACH (Regulation (EC) No 1907/2006) is not proposed by the registrant as PMVE is a gas at ambient condition with a limited water solubility and an high tendency to rapidly volatilise from water to the air. Due to the gaseous nature of the substance and the consequent difficulty to appropriately test PMVE and provide meaningful results testing for bioaccumulation in aqueous media is not proposed.
Moreover, on the basis of the properties of PMVE, in case of release, the substance is expected to primarily and rapidly distribuite to the atmosphere. No significant exposure of aquatic compartment is expected, therefore the assessment of the bioaccumulative properties in water compartment is not considered relevant for PMVE.

Key value for chemical safety assessment

Additional information

PMVE is a gas at ambient condition with limited water solubility and a high tendency to rapidly volatilize from water to the air.

Due to the gaseous nature of the substance and its distribution to the atmosphere, as well as the consequent difficulty to appropriately test PMVE and provide meaningful results, no experimental bioaccumulation data are available and no testing is proposed by the Registrants.

However, in order to evaluate the bioaccumulation hazard profile of PMVE despite the fact that it is expected to rapidly partition to the atmospheric compartment, the BCFBAF (v.3.00, EPI Suite v.4.0) has been be applied.

 The model prediction for PMVE yielded a BCF of 3.993 and a log Kowof 1.42.

According to Annex XIII of Regulation (EC) No 1907/2006 and to the Guidance on information requirements and chemical safety assessment Chapter R.11 (PBT Assessment, May 2008), a substance does not fulfil the criterion “bioaccumulative (B) ” or “very bioaccumulative (vB) ” if the BCF is below 2000 and 5000, respectively, or the log Kow is below 4.5, therefore PMVE is not expected to be bioaccumulative.