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Environmental fate & pathways


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Description of key information

Based on the physico-chemical properties and the environmental fate assessments of the molecule, hydrolitic degradation of PMVE is neither measurable nor expected.

Key value for chemical safety assessment

Additional information

PMVE was assessed both for its physico-chemical properties and for its environmental fate. On the grounds of these assessments, the hydrolytic degradation of PMVE is neither measurable nor expected. In fact the substance is a gas at ambient conditions with a strong tendency to distribute almost exclusively into the atmosphere. According to section 2 of REACh Annex XI, testing for hydrolysis may be omitted since it is technically not possible to conduct the study on a gas. Moreover, the Guidance on Information Requirements and Chemical Safety Assessment Chapter R.7a: Endpoint Specific Guidance, Appendix R.7.1-4 indicates that substances with a Henry's Law constant of around 1 hPa m3/mole rapidly volatilise from water. The Henry’s Law constant of PMVE was calculated to be 32.100 Pa m3/mol (HENRYWIN v3.20, EPI Suite v4.0), suggesting that the substance is expected to rapidly volatilise from water and soil to the air.

In any case, although no distribution into water is expected, the tendency to hydrolyze has been assessed basing on the chemical structure of the PMVE molecule. This does not contain any functional group associated with hydrolysis properties at relevant environmental conditions. Particularly, the carbon-fluorine bond is the strongest bond in organic chemistry (O'Hagan, 2008). Substitution of hydrogen atoms with fluorine results in increased bond strengths for both carbon-fluorine and adjacent carbon-carbon bonds over the corresponding hydrocarbon and would increase the resistance to hydrolysis (Lemal, 2003). Therefore, based on this qualitative structure-activity relationship, it can be concluded that hydrolysis is not a relevant degradation mechanism for PMVE.