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EC number: 202-436-9
CAS number: 95-63-6
Pregnant rats were
exposed whole body to vapours of pseudocumene (0, 100, 300, 600, and 900
ppm; 0, 492, 1470, 2950 and 4430 mg/m3), 6 h/day, on gestational days 6
through 20. Significant decrease in maternal body weight gain and food
consumption was observed at concentrations of 600 ppm pseudocumene, or
greater. Foetal toxicity, expressed as significant reduction in foetal
body weight, occurred at 600 and 900 ppm pseudocumene. There was no
evidence of embryolethal or teratogenic effects following inhalation
exposure. In summary, the NOAEC for maternal and developmental toxicity
was 300 ppm for pseudocumene.
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