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Environmental fate & pathways

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No reliable guideline study has been identified for biodegradability, therefore a weight of evidence assessment has been used to determine the biodegradability of 1, 2, 4-trimethylbenzene. Based on the assessment of four studies, Hutchins (1992), Marion and Melaney (1963), Leahy (2003) and CITI (1977), as well as QSAR predictions (Biowin and BioHCwin) and read across from m-xylene, o-xylene and p-xylene, structural analogues, the substance is considered to be biodegradable and would not be persistent in the environment.