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EC number: 216-823-5
CAS number: 1675-54-3
type 1 hour
48 and 72
erythema 1 1 1 0 - 0.7
edema 0 0 0 0 - 0
erythema 1 1 1 1 0 1
edema 0 0 0 0 0 0
Acute skin irritation/skin corrosion study of Epidian 6 – epoxy resin
with an average molecular mass <=700 to rabbits was performed according
to the agreement with Zakłady Chemiczne ORGANIKA – SARZYNA S.A., Nowa
Sarzyna. The study was coded OS-29/06.
The methodological basis was the OECD Guideline for Testing of Chemicals
No 404/EU Method B.4 as well as Principles of Good Laboratory Practice
(GLP, OECD 1997). The study was performed with white rabbits of New
Zealand strain. The undiluted test material was administered in volume
of 0.5 mL as a single dose to shaved skin of three rabbits and covered
with appropriate band. The exposure time was 4 hours. After 1, 24, 48
and 72 hours as well as 7 and 14 days since the end of exposure time
skin condition was examined.
During observation all test rabbits showed changes on skin in a form of
erythema. Classification of the test material was performed according to
Annex to Decree of Ministry of Health of September 2nd, 2003 (Acts Daily
No 171, Position 1666). Taking into account the obtained results, one
may say that Epidian 6 – epoxy resin with an average molecular mass
<=700 does not irritate skin of rabbits.
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