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EC number: 216-823-5
CAS number: 1675-54-3
Aquatic toxicity testing with BADGE was complicated by the fact that the
test material has a reported water solubility in the range of 0.18 – 11
mg/L, or more generally as < 10 mg/L. This limited
the ability, in some aquatic tests, to specifically determine certain
toxicity endpoints, since adverse effects may not have been observed at
water soluble concentrations. Additionally, several
aquatic toxicity studies were deemed unacceptable for use in the risk
assessment process since the test material was reported to be insoluble
at some or all of the test concentrations used in the study. In
these cases, the test material was reported as a surface film or a
sinking droplet in the test solution. Thus, due to
potential physical effects on the test system and the influence this may
have had on the toxicity results, the studies that reported test
material coming out of solution in this manner were scored as “3 (not
reliable)” and were not used in PNEC derivations.
In regards to BADGE and BADGE-related resins, there were acute toxicity
data sets available for fish, invertebrates and algae, and a chronic
toxicity study with the freshwater invertebrate, Daphnia magna. For
fish, the 96-hour LC50 value of 2.0 mg/L for BADGE and BADGE-related
resins was derived as the geometric mean of four 96-hour LC50 values
taken from valid exposure studies with BADGE and rainbow trout (Oncorhynchus
mykiss). For invertebrates,the 48-hour EC50 value
of 1.8 mg/L for BADGE and BADGE-related resins was derived as the
geometric mean of five 48-hour EC50 values taken from valid exposure
studies with BADGE and Daphnia magna. For the
chronic invertebrate study with D. magna,the 21-day NOEC for
BADGE and BADGE-related resins (based on survival, growth and
reproduction) was 0.3 mg/L. In a growth inhibition
test with Scenedesmus capricornutum,the 72-hour ErC50
for BADGE and BADGE-related resins was determined to be > 11 mg/L, which
was the limit of solubility for BADGE, and the 72-hour NOEC (based on
growth rate) for BADGE and BADGE-related resins was determined to be 4.2
Taken together, the lowest aquatic toxicity value for BADGE and
BADGE-related resins is the 21-day NOEC of 0.3 mg/L based on D. magna growth,
survival and reproduction.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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