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EC number: 246-562-2
CAS number: 25013-15-4
study was conducted to determine the 21 d chronic toxicity of the test
substance to aquatic invertebrates using the EPI SUITE ECOSAR v 1.0 and
1.11 model. The estimated ChV (chronic value) in D. magna was
0.451 mg/L. The ChV corresponds to the geometric mean of the NOEC and
LOEC. Thus, according to ECHA REACH Guidance R.10, the ChV can be
divided by √2 to derive a NOEC. In this case 0.451 mg/L was divided by
root 2 to give a NOEC value of 0.32 mg/L. The same type of model was run
for Mysid saltwater shrimp. The obtained ChV value was 0.098, which
gives a NOEC of 0.07 mg/L. The same values were obtained for the meta-
and para-isomers of the substance. Under the study conditions, the 21 d
NOEC for D. magna and Mysid shrimp were estimated to be 0.32 and
0.07 mg/L, respectively (US EPA, 2017).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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