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Environmental fate & pathways

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Description of key information

Bioaccumulation: aquatic / sediment

BCFBAF model of Estimation Programs Interface was used to predict the bioconcentration factor (BCF) of test chemical. The bioconcentration factor (BCF) of test chemical was estimated to be 70.79 L/kg whole body w.w at 25 °C which does not exceed the bio concentration threshold of 2000, indicating that the test chemical is non bioaccumulative in nature.

Additional information

Bioaccumulation: aquatic / sediment

Various studies predicted have been conducted for test chemical and experimental study was reviewed for its structurally similar read across chemical to determine the bioaccumulation factor of test chemical and their results are summarized below. 

 

In first study the BCFBAF model of Estimation Programs Interface was used to predict the bioconcentration factor (BCF) of test chemical. The bioconcentration factor (BCF) of test chemical was estimated to be 70.79 L/kg whole body w.w at 25 °C .

 

In another study the Bioconcentration Factor (BCF) of test chemical was estimated using Chemspider database. The bioconcentration factor of test chemical was estimated to be 4.18 at both pH 5.5 and 7.4.

 

Next study was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation factor (BCF) value was calculated using a log Kow of 5.82 and a regression-derived equation. The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 600 dimensionless.

 

Last bioaccumulation study in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation factor (BCF) value was calculated using a log Kow of 5.13 and a regression-derived equation. The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 48 dimensionless.

 

By considering results of all the studies mentioned above the BCF value of test chemical was determined to be in range of 4.18 to 600 dimensionless which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical is non bioaccumulative in nature.