Registration Dossier

Ecotoxicological information

Long-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
long-term toxicity to fish, other
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Justification for type of information:
Data is from secondry source
Qualifier:
according to
Guideline:
OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study)
Principles of method if other than guideline:
Long term toxicity study of test material on Oncorhynchus mykiss
GLP compliance:
not specified
Specific details on test material used for the study:
1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., hydroxides, inner salts/61789-40-0 / 263-058-8- IUPAC Name: 1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., hydroxides, inner salts- Common Name: Cocamidopropyl Betaine- Smiles: CCCCCCCCCCCC(=O)NCCCN{+} CC(=O)O{-}
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)
Test type:
static
Water media type:
freshwater
Total exposure duration:
28 h
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
0.16 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
28 d
Dose descriptor:
LOEC
Effect conc.:
0.5 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
mortality
Validity criteria fulfilled:
not specified
Conclusions:
The no effect concentration (NOEC) for the test material 1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., hydroxides, inner salts was observed to be 0.16 mg/l after 28 days of exposure.
Executive summary:

Long term toxicity to fish for 28 days was evaluated for the test material 1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., hydroxides, inner salts on Oncorhynchus mykiss as per OECD 204 Long Term Fish Test.

The no effect concentration (NOEC) and low effect concentration (LOEC) after 28 days was observed to be 0.16 mg/l and 0.5 mg/l respectively. Hence on, the basis of above no effect concentation it can be considered that 1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., hydroxides, inner salts can be classified as aquatic chronic 3 for long term toxicity to fish.

Description of key information

Long term toxicity to fish:

Long term toxicity to fish for 28 days was evaluated for the test material 1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., hydroxides, inner salts on Oncorhynchus mykiss as per OECD 204 Long Term Fish Test.

The no effect concentration (NOEC) and low effect concentration (LOEC) after 28 days was observed to be 0.16 mg/l and 0.5 mg/l respectively. Hence on, the basis of above no effect concentation it can be considered that 1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., hydroxides, inner salts can be classified as aquatic chronic 3 forlong term toxicity to fish.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
0.16 mg/L

Additional information

Long term toxicity to fish:

Long term toxicity to fish for 28 days was evaluated for the test material 1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., hydroxides, inner salts on Oncorhynchus mykiss as per OECD 204 Long Term Fish Test.

The no effect concentration (NOEC) and low effect concentration (LOEC) after 28 days was observed to be 0.16 mg/l and 0.5 mg/l respectively. Hence on, the basis of above no effect concentation it can be considered that 1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., hydroxides, inner salts can be classified as aquatic chronic 3 for long term toxicity to fish.