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Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Data is from handbook and secondary source
Qualifier:
according to guideline
Guideline:
other: OECD 202 Daphnia Reproduction Test
GLP compliance:
not specified
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
Daphnia magna
Test type:
semi-static
Water media type:
freshwater
Total exposure duration:
21 d
Reference substance (positive control):
not specified
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.9 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
reproduction
Duration:
21 d
Dose descriptor:
LOEC
Effect conc.:
3.6 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
reproduction
Validity criteria fulfilled:
not specified
Conclusions:
The no observed effected concentration (NOEC) and low observed effect concentration (LOEC) was observed to be 0.9 mg/l and 3.6 mg/l respectively
Executive summary:

An experiment was conducted to determine the Long term toxicity of test chemical to aquatic invertebrates according toOECD 202 Daphnia Reproduction Test.  The test organism used in this study was Daphnia magna. The experiment was conducted in semi-static condition using fresh water. The test chemical was exposed to Daphnia Magna for 21 days. The no observed effected concentration (NOEC) and low observed effect concentration (LOEC) was observed to be 0.9 mg/l and 3.6 mg/l respectively. By considering the LOEC value test chemical is considered to be non toxic to aquatic invertebrates and cannot be classified as per CLP regulation

Description of key information

An experiment was conducted to determine the Long term toxicity of test chemical to aquatic invertebrates according toOECD 202 Daphnia Reproduction Test.  The test organism used in this study was Daphnia magna. The experiment was conducted in semi-static condition using fresh water. The test chemical was exposed to Daphnia Magna for 21 days. The no observed effected concentration (NOEC) and low observed effect concentration (LOEC) was observed to be 0.9 mg/l and 3.6 mg/l respectively. By considering the LOEC value test chemical is considered to be non toxic to aquatic invertebrates and cannot be classified as per CLP regulation

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.9 mg/L

Additional information

An experiment was conducted to determine the Long term toxicity of test chemical to aquatic invertebrates according toOECD 202 Daphnia Reproduction Test.  The test organism used in this study was Daphnia magna. The experiment was conducted in semi-static condition using fresh water. The test chemical was exposed to Daphnia Magna for 21 days. The no observed effected concentration (NOEC) and low observed effect concentration (LOEC) was observed to be 0.9 mg/l and 3.6 mg/l respectively. By considering the LOEC value test chemical is considered to be non toxic to aquatic invertebrates and cannot be classified as per CLP regulation